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Jian Zhang Selected Research

Small Interfering RNA (siRNA)

8/2023Supermolecular nanovehicles co-delivering TLR7/8-agonist and anti-CD47 siRNA for enhanced tumor immunotherapy.
1/2023Aspirin increases chemosensitivity of colorectal cancer cells and inhibits the expression of toll-like receptor 4.
1/2023Neuralized1-Mediated CPEB3 Ubiquitination in the Spinal Dorsal Horn Contributes to the Pathogenesis of Neuropathic Pain in Rats.
10/2022LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis.
3/2022Calming egress of inflammatory monocytes and related septic shock by therapeutic CCR2 silencing using macrophage-derived extracellular vesicles.
11/2021KDM6B epigenetically regulated-interleukin-6 expression in the dorsal root ganglia and spinal dorsal horn contributes to the development and maintenance of neuropathic pain following peripheral nerve injury in male rats.
10/2021Inhibition of CDC42 reduces macrophage recruitment and suppresses lung tumorigenesis in vivo.
9/2021Endogenous microRNA triggered enzyme-free DNA logic self-assembly for amplified bioimaging and enhanced gene therapy via in situ generation of siRNAs.
7/2021Autophagy Modulation and Synergistic Therapy to Combat Multidrug Resistance Breast Cancer Using Hybrid Cell Membrane Nanoparticles.
6/2021Screening for alternative splicing of lncRNA Dleu2 in the mouse liver cell line AML-12.
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Jian Zhang Research Topics

Disease

1134Neoplasms (Cancer)
05/2024 - 07/2002
197Breast Neoplasms (Breast Cancer)
05/2024 - 02/2002
196Inflammation (Inflammations)
05/2024 - 11/2004
161Neoplasm Metastasis (Metastasis)
04/2024 - 04/2002
158Infections
05/2024 - 11/2002
118Hepatocellular Carcinoma (Hepatoma)
04/2024 - 12/2003
104Carcinogenesis
01/2024 - 07/2003
99Lung Neoplasms (Lung Cancer)
02/2024 - 12/2004
93Heart Failure
06/2024 - 06/2002
84Fibrosis (Cirrhosis)
05/2024 - 08/2003
79Necrosis
03/2024 - 12/2004
75Hypoxia (Hypoxemia)
04/2024 - 10/2007
74Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2024 - 12/2002
69Myocardial Infarction
12/2023 - 05/2005
64Colorectal Neoplasms (Colorectal Cancer)
05/2024 - 04/2002
62Stomach Neoplasms (Stomach Cancer)
04/2024 - 09/2006
60Prostatic Neoplasms (Prostate Cancer)
03/2023 - 10/2003
57Carcinoma (Carcinomatosis)
12/2023 - 10/2003
52Pain (Aches)
04/2024 - 04/2005
52Body Weight (Weight, Body)
02/2024 - 06/2003
50Wounds and Injuries (Trauma)
04/2024 - 08/2003
48Alzheimer Disease (Alzheimer's Disease)
03/2024 - 09/2003
48Glioma (Gliomas)
10/2023 - 04/2008
45Stroke (Strokes)
03/2024 - 12/2004
43Cardiovascular Diseases (Cardiovascular Disease)
01/2024 - 07/2006
41Adenocarcinoma of Lung
03/2024 - 04/2008
41Nasopharyngeal Carcinoma
02/2024 - 04/2011
40Reperfusion Injury
01/2024 - 05/2007
39Ischemia
03/2024 - 01/2006
39Infarction (Infarctions)
01/2024 - 05/2005
37Hemorrhage
04/2024 - 11/2003
36Obesity
04/2024 - 02/2004
34COVID-19
05/2024 - 01/2020
34Osteosarcoma (Osteogenic Sarcoma)
03/2024 - 10/2003
33Glioblastoma (Glioblastoma Multiforme)
02/2024 - 08/2008
33Triple Negative Breast Neoplasms
01/2024 - 02/2014
32Thrombosis (Thrombus)
01/2024 - 04/2005
31Colonic Neoplasms (Colon Cancer)
04/2024 - 02/2005
31Ischemic Stroke
03/2024 - 07/2010
31Hypertension (High Blood Pressure)
03/2024 - 03/2007
31Type 2 Diabetes Mellitus (MODY)
12/2023 - 01/2007
30Disease Progression
04/2024 - 11/2008
30Asthma (Bronchial Asthma)
06/2023 - 04/2005
29Adenocarcinoma
03/2024 - 02/2005
29Cognitive Dysfunction
01/2024 - 02/2006
28Pancreatic Neoplasms (Pancreatic Cancer)
11/2023 - 09/2008
27Leukemia
12/2023 - 06/2005
26Myocardial Ischemia (Ischemic Heart Diseases)
12/2023 - 05/2007
25Small Cell Lung Carcinoma (Small Cell Lung Cancer)
05/2024 - 08/2015
25Neuroinflammatory Diseases
03/2024 - 09/2007

Drug/Important Bio-Agent (IBA)

386Proteins (Proteins, Gene)FDA Link
05/2024 - 07/2002
220Biomarkers (Surrogate Marker)IBA
05/2024 - 07/2005
141MicroRNAs (MicroRNA)IBA
04/2024 - 06/2010
133Messenger RNA (mRNA)IBA
05/2024 - 08/2002
118CytokinesIBA
05/2024 - 01/2003
81RNA (Ribonucleic Acid)IBA
05/2024 - 10/2008
80EnzymesIBA
05/2024 - 07/2002
74Long Noncoding RNAIBA
01/2024 - 08/2014
72DNA (Deoxyribonucleic Acid)IBA
01/2023 - 08/2002
63Immune Checkpoint InhibitorsIBA
05/2024 - 01/2018
61AntigensIBA
11/2023 - 02/2002
60Peptides (Polypeptides)IBA
05/2024 - 09/2003
60Glucose (Dextrose)FDA LinkGeneric
01/2024 - 03/2004
56Therapeutic UsesIBA
12/2023 - 03/2004
54LigandsIBA
12/2023 - 01/2003
52Small Interfering RNA (siRNA)IBA
08/2023 - 06/2006
50Transcription Factors (Transcription Factor)IBA
05/2024 - 06/2007
48Interleukin-6 (Interleukin 6)IBA
04/2023 - 02/2006
45Cisplatin (Platino)FDA LinkGeneric
05/2024 - 12/2002
43Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2023 - 11/2003
42Hormones (Hormone)IBA
02/2024 - 05/2003
41LipidsIBA
11/2023 - 02/2004
37Doxorubicin (Adriamycin)FDA LinkGeneric
05/2024 - 08/2011
36LipopolysaccharidesIBA
03/2024 - 06/2003
36CateninsIBA
12/2023 - 02/2012
35CollagenIBA
04/2024 - 01/2003
35Phosphotransferases (Kinase)IBA
01/2024 - 07/2010
34Circular RNAIBA
02/2024 - 01/2019
33Reactive Oxygen Species (Oxygen Radicals)IBA
05/2024 - 12/2009
32AntioxidantsIBA
05/2024 - 11/2004
32Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2022 - 02/2004
31Oxygen (Dioxygen)IBA
03/2024 - 05/2006
30VaccinesIBA
01/2024 - 03/2007
29pro-brain natriuretic peptide (1-76)IBA
01/2024 - 05/2006
29Interleukin-10 (Interleukin 10)IBA
05/2023 - 01/2003
28Indicators and Reagents (Reagents)IBA
04/2024 - 01/2010
28ErbB Receptors (EGF Receptor)IBA
03/2024 - 05/2008
27Insulin (Novolin)FDA Link
02/2024 - 09/2003
26Antiviral Agents (Antivirals)IBA
08/2023 - 07/2011
25ChemokinesIBA
12/2023 - 06/2007
25CholesterolIBA
07/2023 - 09/2003
25Anti-Bacterial Agents (Antibiotics)IBA
10/2022 - 02/2004

Therapy/Procedure

485Therapeutics
05/2024 - 10/2003
193Drug Therapy (Chemotherapy)
05/2024 - 04/2002
140Immunotherapy
04/2024 - 04/2004
80Radiotherapy
05/2024 - 12/2008
48Transplantation
02/2024 - 10/2003
27Stents
08/2023 - 04/2005
27Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2022 - 06/2007
25Liver Transplantation
04/2024 - 08/2007